Is Estrogen Causing Your Stuffy Nose? The Shocking Link Between Hormones and Nasal Congestion

Hormonal changes, especially during menopause, can affect your nasal health in surprising ways. Many studies have shown that estrogen, the key hormone in women, plays a big role in nasal symptoms like runny nose and nasal congestion. As estrogen levels change, it can impact the nose in various ways.

For estrogen to have an effect on the body, it has to bind to special receptors. These receptors are found in areas of the nose, particularly the turbinates, which are the structures inside the nostrils. Estrogen receptors are also present in the cells of the nose, like the glandular cells, which help produce mucus. When estrogen binds to these receptors, it can cause changes in the blood vessels and tissues of the nose, leading to increased nasal secretions and congestion.

In one study of 25 women using birth control pills, nearly half of the participants showed changes in their nasal tissue, such as swelling and increased tissue growth. Another study on menopausal women found that they had fewer of the glands that produce mucus in the nose compared to younger women.

Research has shown that the nose, just like the vagina, reacts to hormone levels. During certain times of the month, when estrogen levels are higher (like during the follicular phase or early ovulation), the nose can be more affected by estrogen. The amount of estrogen in the body can change how the nasal tissues respond.

One study also found that women in the early luteal phase (when estrogen is still high) had more nasal congestion and ear problems compared to when their estrogen levels were lower in the early follicular phase. Estrogen can also cause blood vessels in the nose to expand, which leads to more mucus production and a stuffy nose. This is often seen in pregnant women, who experience “rhinitis of pregnancy,” especially in the third trimester. This condition causes severe nasal congestion and a blocked nose.

Young children going through puberty may also experience more nosebleeds, as hormonal changes can cause the nasal tissues to become more sensitive.

There is hope that hormone therapy could help prevent or treat nasal problems in postmenopausal women, but more research is needed. Additionally, birth control pills are sometimes listed as a cause of nasal symptoms in people with non-allergic rhinitis.

Understanding how hormones, like estrogen, affect nasal health can help people better manage symptoms like runny nose and nasal congestion, especially during periods of hormonal changes like menopause.


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2.         Millas, I., Liquidato, B. M., de Sousa Buck, H., Barros, M. D., Paes, R. A. P., & Dolci, J. E. L. (2011). Evaluation of estrogenic receptors in the nasal mucosa of women taking oral contraceptives. Contraception (Stoneham)83(6), 571–577. New York, NY: Elsevier Inc.

3.         Monti-Bloch L, Jennings-White C, Dolberg DS, Berliner DL. The human vomeronasal system. Psychoneuroendocrinology. 1994;19(5-7):673-86. doi: 10.1016/0306-4530(94)90049-3. PMID: 7938363.

4.         Yang, X., Zhane, R. B., Eremeeva, K. V., Svistushkin, V. M., & Smolyarchuk, E. A. (2024). Effects of Female Sex Hormone Therapy on Nasal Mucosa. Indian journal of otolaryngology, and head, and neck surgery.

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